Enantiomeric separation of biaryl atropisomers using cyclofructan based chiral stationary phases
نویسندگان
چکیده
منابع مشابه
A validated chiral LC method for enantiomeric separation of intermediate of lopinavir by using cellulose based chiral stationary phase
2R-(1-Tetrahydro pyrimid-2-onyl)-3-methyl butanoic acid. (STHPA) (Figure 1) is a intermediate for Lopinavir (Figure 2). Lopinavir is antiretroviral drugs acting as inhibitors of human immunodeficiency virus (HIV) protease, a class of drugs that has markedly improved morbidity and mortality of HIV infected patients[1]. Within the highly active antiretroviral therapy (HAART) they are used in a f...
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ژورنال
عنوان ژورنال: Journal of Chromatography A
سال: 2014
ISSN: 0021-9673
DOI: 10.1016/j.chroma.2014.04.080